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CD163 抗体

This anti-CD163 antibody is a 小鼠 单克隆 antibody detecting CD163 in WB, FACS, IP 和 IHC (fro). Suitable for 人.
产品编号 ABIN781802
发货至: 中国

Quick Overview for CD163 抗体 (ABIN781802)

抗原

See all CD163 抗体
CD163

适用

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宿主

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小鼠

克隆类型

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  • 1
单克隆

标记

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This CD163 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

GHI-61
  • 特异性

    This antibody recognizes CD163, an approximately 130 kDa high affinity scavenger receptor expressed mainly on monocytes and macrophages, which binds hemoglobin-haptoglobin complex.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Protein-A affinity chromatography

    纯度

    > 95 % pure (by SDS-PAGE)

    免疫原

    Hairy cell leukemia cells

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.4, 15 mM Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原

    CD163

    别名

    CD163

    背景

    CD163, also known as M130, is a member of the scavenger receptor family, accounting for the clearance of hemoglobin-haptoglobin complexes during limited hemolysis, which protects the body, in particular the kidneys, against heme-mediated oxidative damages. It does not have measurable affinity for noncomplexed hemoglobin or haptoglobin. Immunomodulatory role of CD163 has been postulated. CD163 is expressed by cells of the monocyte-macrophage lineage and its extracellular part also circulates in plasma as a soluble protein, especially during sepsis and other conditions affecting macrophage activity, when its level may raise manyfold.Synonyms: Hemoglobin scavenger receptor, M130, Macrophage marker, Scavenger receptor cysteine-rich type 1 protein M130

    基因ID

    9332

    NCBI登录号

    NP_004235

    UniProt

    Q86VB7
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